Research on the anti-aging mechanism of algae components in the ocean on skin

Research on the anti-aging mechanism of algae components in the ocean on skin

The skin is exposed to various external factors that cause skin aging, among which oxidative stress plays a key role. Reactive oxygen species (ROS) are the main culprits of oxidative stress, causing cell damage and damaging the appearance of the skin. Oxidative degradation of lipid membranes can negatively impact the overall condition of the skin, and as the body ages, its ability to regulate these reactive oxygen species is compromised, leading to increased mitochondrial production and ultimately skin aging. To counteract this process, MOOMNA is researching the use of antioxidants in experimental formulations to reduce oxidative stress and its harmful effects. Previous research from MOOMNA Labs has highlighted the importance of antioxidants in combating skin aging.

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Exposure to solar radiation is the main source of ROS production, and ultraviolet rays hinder the activity of antioxidant enzymes, further exacerbating oxidative stress. Therefore, prolonged exposure to solar radiation is considered a major cause of skin aging, leading to manifestations such as hyperpigmentation and photoaging, which are characterized by degradation of collagen and hyaluronic acid, ultimately leading to the formation of wrinkles and dry skin.

In this context, the use of marine ingredients holds promise due to their rich antioxidant properties and diverse biological activities that can counteract the damaging effects of reactive oxygen species (ROS). Macroalgae, commonly called seaweed, include various taxa such as Rhodophycea (red algae), Phaeophyceae (brown algae), and Chlorophyceae (green algae). These organisms are highlighted by Moomna Labs because of their biodegradable and non-toxic nature, making them a valuable source of natural compounds with a variety of biological activities. Seaweed is rich in polysaccharides such as fucoidan, which has antioxidant, immunomodulatory and anti-aging properties.

Our research focused specifically on the benefits of ingredients containing Fucus extract, Ulva extract and Ectoin, all of which are sourced from the ocean. These ingredients have been extensively researched and shown to have potential benefits for skin health, including slowing skin aging, preventing oxidative stress, and maintaining skin barrier function. Previous studies have highlighted the bioactivity of seaweed, emphasizing its ability to slow down skin aging, exhibit antioxidant activity and possess immunomodulatory properties. Seaweed is also known for its high polysaccharide content, such as fucoidan, which has antioxidant and anti-inflammatory properties.

By incorporating these marine ingredients into our latest formulas, we aim to harness their antioxidant properties and evaluate their impact on various skin parameters, including hydration, barrier function and wrinkle reduction. New formulation research combines Fucus extract, Ulva extract and Ectoin to provide a unique blend of bioactive compounds with potentially synergistic effects. This allows us to take a more holistic approach to address multiple aspects of skin aging and combat the damaging effects of reactive oxygen species.

Research on fucoidan derived from seaweed extracts has demonstrated its potential as a cosmetic ingredient with anti-aging activity. In vitro studies have shown that fucoidan can inhibit collagenase and elastase, two enzymes that play key roles in skin aging. Additionally, fucoidan has shown immunomodulatory properties and was found to increase levels of the SIRT1 protein, which is involved in maintaining skin function. The polyphenol-rich extract of Fucus algae has shown significant antioxidant value, preventing oxidative damage on the skin surface. Additionally, fucoidan has been shown to promote fibroblast proliferation, collagen deposition, and protect the skin’s elastic fiber network in vitro. It also shows potential in modulating the activity and secretion of matrix metalloproteinases (MMPs), inhibiting tyrosinase activity, and displaying anti-melanogenic properties. These anti-aging properties are consistent with our research into improving skin hydration and reducing wrinkles.


Preclinical and clinical applications further support the efficacy of macroalgae ingredients. For example, Fucus algae has been shown to have soothing and protective effects in the body against UV damage. A systematic review of the scientific literature also highlights the clinical safety and efficacy of macroalgae-based skin care products, particularly in terms of moisturizing, anti-melanogenesis, and anti-cellulite. Likewise, Ulva (a type of green algae) also displays significant antioxidant activity and the ability to protect skin cells from oxidative damage caused by UV radiation. It also has anti-inflammatory properties and the ability to stimulate collagen production, potentially reducing the appearance of fine lines and wrinkles.

In our study, we specifically evaluated the efficacy of the newest formulas compared to moisturizer alone, focusing on skin barrier function, hydration, and skin roughness. Our results show that the new formulation has significant anti-wrinkle effects, with reduced skin roughness compared to baseline measurements. Subjects’ barrier function remained stable and within normal limits, as measured by transcutaneous water loss

In addition, moomna Laboratories is working on effectively lowering skin pH to an average pH of <5 in the latest anti-aging formulas. pH is a key factor in various metabolic, molecular, and cellular regulatory processes, especially in the stratum corneum, where it is essential for the physical, chemical, and microbial barrier functions of the skin. Skin pH varies on different parts of the body, typically ranging from moderately acidic (pH 4.1-5.8) as the “normal” pH for the skin surface, with an average of 4.9. Skin pH is affected by factors such as age, gender, race, anatomical location, circadian rhythm, sebum production, skin moisture and sweating. Various external factors, including occlusion, exposure to skin irritants such as soaps and detergents, and skin washing, can affect the pH of the skin. Additionally, the use of cosmetics can increase the pH of the skin, as many cosmetics have a pH higher than the skin’s natural pH. Even using tap water (which in Europe usually has a pH of about 8.0) temporarily increases the skin’s pH for up to 6 hours before returning to its natural level of less than 5.0 on average.

Our research demonstrates the moisturizing and anti-wrinkle benefits of ingredients containing Fucus extract, Ulva extract and Ectoin. This is the first study of the synergistic effects of related ingredients. Our findings will contribute to the body of knowledge about marine skin care formulations and highlight the potential benefits of using multiple marine ingredients simultaneously. Of course, further research is needed to explore the long-term effects and mechanisms of action of this unique combination in skin care applications.

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皮肤暴露于各种导致皮肤老化的外部因素,其中氧化应激在其中发挥着关键作用。活性氧 (ROS) 是氧化应激的罪魁祸首,会导致细胞损伤并损害皮肤外观。脂质膜的氧化降解会对皮肤的整体状况产生负面影响,并且随着身体年龄的增长,其调节这些活性氧的能力会受到损害,导致线粒体生成增加,最终导致皮肤老化。为了抵消这一过程,moomna正在研究尝试在实验配方中加入抗氧化剂对于减轻氧化应激及其有害影响。moomna实验室先前的研究强调了抗氧化剂在对抗皮肤衰老方面的重要性。





针对源自海藻提取物的岩藻依聚糖的研究已证明其作为具有抗衰老活性的化妆品成分的潜力。体外研究表明,岩藻依聚糖可以抑制胶原酶和弹性蛋白酶,这两种酶在皮肤老化中起关键作用。此外,岩藻依聚糖已显示出免疫调节特性,并被发现可以提高 SIRT1 蛋白的水平,该蛋白参与维持皮肤功能。墨角藻富含多酚的提取物已显示出显着的抗氧化价值,可防止皮肤表面的氧化损伤。此外,岩藻依聚糖已被证明可以促进成纤维细胞增殖、胶原蛋白沉积,并在体外保护皮肤的弹性纤维网络。它还在调节基质金属蛋白酶 ( MMP ) 的活性和分泌、抑制酪氨酸酶活性和显示抗黑色素生成特性方面表现出潜力。这些抗衰老特性与我们的研究结果相符,这些深入研究有助于改善我们皮肤水合和减少皱纹。




此外,moomna实验室正在致力于在最新抗衰老配方中有效降低皮肤pH值至平均pH值<5。 pH 值是各种代谢、分子和细胞调节过程中的关键因素,特别是在角质层中,它对于皮肤的物理、化学和微生物屏障功能至关重要。身体不同部位的皮肤 pH 值各不相同,通常范围为中度酸性(pH 4.1-5.8)作为皮肤表面的“正常”pH 值,平均值为 4.9。皮肤的pH值受年龄、性别、种族、解剖位置、昼夜节律、皮脂产生、皮肤湿度和出汗等因素的影响。各种外部因素,包括闭塞、接触肥皂和清洁剂等皮肤刺激物以及皮肤清洗,都会影响皮肤的 pH 值。此外,化妆品的使用会提高皮肤的 pH 值,因为许多化妆品的 pH 值高于皮肤的自然 pH 值。即使使用自来水(在欧洲 pH 值通常约为 8.0),也会暂时增加皮肤的 pH 值长达 6 小时,然后平均恢复到低于 5.0 的自然水平。




皮膚暴露於各種導致皮膚老化的外部因素,其中氧化壓力在其中發揮關鍵作用。 活性氧 (ROS) 是氧化壓力的罪魁禍首,會導致細胞損傷並損害皮膚外觀。 脂質膜的氧化降解會對皮膚的整體狀況產生負面影響,隨著身體年齡的增長,其調節這些活性氧的能力會受到損害,導致粒線體生成增加,最終導致皮膚老化。 為了抵消這個過程,moomna正在研究嘗試在實驗配方中添加抗氧化劑對於減輕氧化壓力及其有害影響。 moomna實驗室先前的研究強調了抗氧化劑在對抗皮膚老化方面的重要性。

暴露在太陽輻射下是ROS產生的主要來源,紫外線會阻礙抗氧化酶的活性,進一步加劇氧化壓力。 因此,長時間暴露在太陽輻射下被認為是皮膚老化的主要原因,導致色素沉著過度和光老化等表現,其特徵是膠原蛋白和透明質酸降解,最終導致皺紋和皮膚乾燥的形成。

在這種背景下,海洋成分的使用因其豐富的抗氧化特性和多樣化的生物活性而具有前景,可以抵消活性氧(ROS)的破壞作用。 大型藻類,通常稱為海藻,包括各種分類群,例如紅藻(紅藻)、褐藻(褐藻)和綠藻綱(綠藻)。 這些生物體因其可生物降解和無毒的性質而被moomna實驗室重點研究,使其成為具有多種生物活性的天然化合物的寶貴來源。 海藻中富含岩藻依聚醣等多醣,具有抗氧化、免疫調節及延緩皮膚老化的特性

我們的研究特別關注含有墨角藻萃取物、石蓴萃取物和依克多因的功效,所有這些成分均源自海洋。 這些成分已被廣泛研究並證明對皮膚健康具有潛在益處,包括延緩皮膚老化、防止氧化壓力和維持皮膚屏障功能。 先前的研究強調了海藻的生物活性,強調其延緩皮膚老化、表現出抗氧化活性並具有免疫調節特性的能力。 海藻也以其高多醣含量而聞名,例如岩藻依聚醣,它具有抗氧化和抗發炎特性。

透過將這些海洋成分融入我們的最新配方中,我們的目標是利用它們的抗氧化特性並評估它們對各種皮膚參數的影響,包括水合作用、屏障功能和減少皺紋。 新的配方研究結合了墨角藻萃取物、石蓴萃取物和依克多因,提供了具有潛在協同效應的獨特生物活性化合物混合物。 這使得我們能夠採取更全面的方法來解決皮膚老化的多個方面並對抗活性氧的破壞性影響。

針對源自海藻萃取物的岩藻依聚醣的研究已證明其作為具有抗衰老活性的化妝品成分的潛力。 體外研究表明,岩藻依聚醣可以抑制膠原蛋白酶和彈性蛋白酶,這兩種酶在皮膚老化中起關鍵作用。 此外,岩藻依聚醣已顯示出免疫調節特性,並被發現可以提高 SIRT1 蛋白的水平,該蛋白參與維持皮膚功能。 墨角藻富含多酚的萃取物已顯示出顯著的抗氧化價值,可防止皮膚表面的氧化損傷。 此外,岩藻依聚醣已被證明可以促進纖維母細胞增殖、膠原蛋白沉積,並在體外保護皮膚的彈性纖維網絡。 它還在調節基質金屬蛋白酶 ( MMP ) 的活性和分泌、抑制酪氨酸酶活性和顯示抗黑色素生成特性方面表現出潛力。 這些抗衰老特性與我們的研究結果相符,這些深入研究有助於改善我們皮膚水合和減少皺紋。


臨床前和臨床應用進一步支持了大型藻類成分的功效。 例如,墨角藻已在體內表現出針對紫外線損傷的舒緩和保護作用。 科學文獻的系統性回顧也強調了基於大型藻類的護膚產品的臨床安全性和功效,特別是在保濕、抗黑色素生成和抗脂肪團方面的功效。 同樣,石蓴(一種綠藻)也顯示出顯著的抗氧化活性和保護皮膚細胞免受紫外線輻射造成的氧化損傷的能力。 它還具有抗炎特性和刺激膠原蛋白生成的能力,從而有可能減少細紋和皺紋的出現。

在我們的研究中,我們專門評估了最新配方與單獨保濕霜相比的功效,重點是皮膚屏障功能、水合作用和皮膚粗糙度。 我們的研究結果表明,新配方具有顯著的抗皺效果,與基線測量相比,皮膚粗糙度降低。 根據經皮失水測量結果顯示,受試者的屏障功能保持穩定並在正常範圍內

此外,moomna實驗室正在致力於在最新抗衰老配方中有效降低皮膚pH值至平均pH值<5。 pH 值是各種代謝、分子和細胞調節過程中的關鍵因素,特別是在角質層中,它對於皮膚的物理、化學和微生物屏障功能至關重要。 身體不同部位的皮膚 pH 值各不相同,通常範圍為中度酸性(pH 4.1-5.8)作為皮膚表面的「正常」pH 值,平均值為 4.9。 皮膚的pH值受年齡、性別、種族、解剖位置、晝夜節律、皮脂產生、皮膚濕度和出汗等因素的影響。 各種外部因素,包括閉塞、接觸肥皂和清潔劑等皮膚刺激物以及皮膚清洗,都會影響皮膚的 pH 值。 此外,化妝品的使用會提高皮膚的 pH 值,因為許多化妝品的 pH 值高於皮膚的自然 pH 值。 即使使用自來水(在歐洲 pH 值通常約為 8.0),也會暫時增加皮膚的 pH 值長達 6 小時,然後平均恢復到低於 5.0 的自然水平。

我們的研究證明了含有墨角藻萃取物、石蓴萃取物和依克多因成分的使用具有保濕和抗皺功效。 這是第一次對於相關成分的協同效應的研究。 我們的研究結果將有助於豐富有關海洋護膚配方的知識體系,並強調同時使用多種海洋成分的潛在好處。 當然我們還需要進一步的研究來探索這種獨特組合在護膚應用中的長期效果和作用機制。